Biomedical devices that contact with blood or tissue represent a wide range of products. Depending on their potential harm to a body, medical devices are categorized according to the degree, so their safety can be assured. All biomaterials are by definition designed to contact with a body for a certain period of time. The nature of the body contact, as well as the duration a material contacts with the body may initiate unwanted biological In comparison with invasive devices Oike catheters and medical responses. implants contact directly with tissue or with the circulating blood) non invasive devices (like wound-dressings and contact lenses contact with the skin, the sclera, and the mucosa or with open wounds) have a lesser risk of hurting a patient. When blood contacts with a foreign material, plasma proteins become absorpted to the surface within a few seconds. The reactions that follow, the so-called intrinsic pathway lead to the formation of fibrin and activation of platelets and white blood cells, result in blood clot formation.
This book provides a comprehensive approach to studying the principles and design of biomedical devices and their applications in medicine. It is written for engineers and technologists who are interested in understanding the principles, design, and use of medical device technology. The book is also intended to be a textbook or reference for biomedical device technology courses in universities and colleges. It focuses on the applications, functions and principles of medical devices (which are the invariant components) and uses specific designs and constructions to illustrate the concepts where appropriate. Indication of use as well as common problems and hazards for each device type are included. This book selectively covers diagnostic and therapeutic devices that are either commonly used or whose principles and design represent typical applications of the technology. For those who would like to know more, a collection of published papers and book references has been added to the end of each chapter. In this third edition, many chapters have gone through revisions, some with significant updates and additions, to keep up with new applications and advancements in medical technology. A new appendix on infection prevention and control practices relating to medical devices is included. Based on requests, review questions are added for each chapter to help readers to assess their comprehension of the content material.
This textbook provides essential knowledge for biomedical product development, including material properties, fabrication processes and design techniques for different applications, as well as process design and optimization. This book is multidisciplinary and readers can learn techniques to apply acquired knowledge for various applications of biomedical design. Further, this book encourages readers to discover and convert newly reported technologies into products and services for the future development of biomedical applications. This is an ideal book for upper-level undergraduate and graduate students, engineers, technologists, and researchers working in the area of biomedical engineering and manufacturing. This book also: Provides a comprehensive set of fundamental knowledge for engineering students and entry level engineers to design biomedical devices Offers a unique approach to manufacturing of biomedical devices by integrating and formulating different considerations in process design tasks into optimization problems Provides a broad range of application examples to guide readers through the thinking process of designing and manufacturing biomedical devices, from basic understanding about the requirements and regulations to a set of manufacturing parameters
This book presents a road map for applying the stages in conceptualization, evaluation, and testing of biomedical devices in a systematic order of approach, leading to solutions for medical problems within a well-deserved safety limit. The issues discussed will pave the way for understanding the preliminary concepts used in modern biomedical device engineering, which include medical imaging, computational fluid dynamics, finite element analysis, particle image velocimetry, and rapid prototyping. This book would undoubtedly be of use to biomedical engineers, medical doctors, radiologists, and any other professionals related to the research and development of devices for health care.
Metals for Biomedical Devices, Second Edition, has been fully updated and builds upon the success of its first edition, discussing the latest techniques in metal processing methods and the behavior of this important material. Initial chapters review the current status and selection of metals for biomedical devices. Subsequent chapters cover mechanical behavior, degradation and testing, corrosion, wear testing and biocompatibility, the processing of metals for biomedical applications, including topics such as forging metals and alloys, surface treatment, coatings and sterilization. Chapters in the final section discuss the clinical applications of metals, such as cardiovascular, orthopedic and new generation biomaterials. With its distinguished editor and team of expert contributors, this book is a standard reference for materials scientists, researchers and engineers working in the medical devices industry and academia. Reviews the latest techniques in metal processing methods, including surface treatment and sterilization Examines metal selection for biomedical devices, considering the biocompatibility of various metals Assesses mechanical behavior and the testing of metals, featuring the latest information on corrosion, fatigue and wear Discusses biodegradable alloys, including a new section on Mg alloys Includes a new section that discusses the use of additive manufacturing in the production of medical devices
Electronic Devices, Circuits, and Systems for Biomedical Applications: Challenges and Intelligent Approaches explains the latest information on the design of new technological solutions for low-power, high-speed efficient biomedical devices, circuits and systems. The book outlines new methods to enhance system performance, provides key parameters to explore the electronic devices and circuit biomedical applications, and discusses innovative materials that improve device performance, even for those with smaller dimensions and lower costs. This book is ideal for graduate students in biomedical engineering and medical informatics, biomedical engineers, medical device designers, and researchers in signal processing. Presents major design challenges and research potential in biomedical systems Walks readers through essential concepts in advanced biomedical system design Focuses on healthcare system design for low power-efficient and highly-secured biomedical electronics
FUNCTIONALIZED CARBON NANOTUBES FOR BIOMEDICAL APPLICATIONS The book highlights established research and technology on current and emerging trends and biomedical applications of functionalized carbon nanotubes by providing academic researchers and scientists in industry, as well as high-tech start-ups, with knowledge of the modern practices that will revolutionize using functionalized carbon nanotubes. Nanotechnology suggests fascinating opportunities for a variety of applications in biomedical fields, including bioimaging and targeted delivery of biomacromolecules into cells. Numerous strategies have been recommended to functionalize carbon nanotubes with raised solubility for efficient use in biomedical applications. Functionalized carbon nanotubes have unique arrangements and extravagant mechanical, thermal, magnetic, optical, electrical, surface, and chemical properties, and the combination of these features gives them widespread biomedical applications. Functionalized carbon nanotubes are relatively flexible and interact with the cell membranes and penetrate different biological tissues owing to a “snaking” effect, therefore both the pharmacological and toxicological profiles of functionalized carbon nanotubes have gathered much attention in recent times. This book covers a broad range of topics relating to carbon nanotubes, from synthesis and functionalization to applications in advanced biomedical devices and systems. As they possess unique and attractive physical, chemical, optical, and even magnetic properties for various applications, considerable effort has been made to employ functionalized carbon nanotubes as new materials for the development of novel biomedical tools, such as diagnostic sensors, imaging agents, and drug/gene delivery systems for both diagnostics and clinical treatment. Audience The book is intended for a very broad audience of researchers and scientists working in the fields of nanomaterials, nanomedicine, bioinspired nanomaterials, nanotechnology, and biomedical application of nanomaterials.
Biomedical Devices: Design, Prototyping, and Manufacturing features fundamental discussions of all facets of materials processing and manufacturing processes across a wide range of medical devices and artificial tissues. Represents the first compilation of information on the design, prototyping, and manufacture of medical devices into one volume Offers in-depth coverage of medical devices, beginning with an introductory overview through to the design, manufacture, and applications Features examples of a variety of medical applications of devices, including biopsy micro forceps, micro-needle arrays, wrist implants, spinal spacers, and fixtures Provides students, doctors, scientists, and technicians interested in the development and applications of medical devices the ideal reference source
Smart polymers are polymers that respond to different stimuli or changes in the environment. Smart Polymers and their Applications reviews the types, synthesis, properties, and applications of smart polymers. Chapters in part one focus on types of polymers, including temperature-, pH-, photo-, and enzyme-responsive polymers. Shape memory polymers, smart polymer hydrogels, and self-healing polymer systems are also explored. Part two highlights applications of smart polymers, including smart instructive polymer substrates for tissue engineering; smart polymer nanocarriers for drug delivery; the use of smart polymers in medical devices for minimally invasive surgery, diagnosis, and other applications; and smart polymers for bioseparation and other biotechnology applications. Further chapters discuss the use of smart polymers for textile and packaging applications, and for optical data storage. Smart Polymers and their Applications is a technical resource for chemists, chemical engineers, mechanical engineers, and other professionals in the polymer industry; manufacturers in such sectors as medical, automotive, and aerospace engineering; and academic researchers in polymer science. Reviews the different types of smart polymer, discussing their properties, structure, design, and characterization Reviews applications of smart polymers in such areas as biomedical engineering, textiles, and food packaging
Apply a Wide Variety of Design Processes to a Wide Category of Design Problems Design of Biomedical Devices and Systems, Third Edition continues to provide a real-world approach to the design of biomedical engineering devices and/or systems. Bringing together information on the design and initiation of design projects from several sources, this edition strongly emphasizes and further clarifies the standards of design procedure. Following the best practices for conducting and completing a design project, it outlines the various steps in the design process in a basic, flexible, and logical order. What’s New in the Third Edition: This latest edition contains a new chapter on biological engineering design, a new chapter on the FDA regulations for items other than devices such as drugs, new end-of-chapter problems, new case studies, and a chapter on product development. It adds mathematical modeling tools, and provides new information on FDA regulations and standards, as well as clinical trials and sterilization methods. Familiarizes the reader with medical devices, and their design, regulation, and use Considers safety aspects of the devices Contains an enhanced pedagogy Provides an overview of basic design issues Design of Biomedical Devices and Systems, Third Edition covers the design of biomedical engineering devices and/or systems, and is designed to support bioengineering and biomedical engineering students and novice engineers entering the medical device market.
As a paradigm for the future, micro-scale technology seeks to fuse revolutionary concepts in science and engineering and then translate it into reality. Nanotechnology is an interdisciplinary field that aims to connect what is seen with the naked eye and what is unseen on the molecular level. The Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering examines the strengths and future potential of micro-scale technologies in a variety of industries. Highlighting the benefits, shortcomings, and emerging perspectives in the application of nano-scale technologies, this book is a comprehensive reference source for synthetic chemists, engineers, graduate students, and researchers with an interest in the multidisciplinary applications, as well as the ongoing research in the field.
From exoskeletons to neural implants, biomedical devices are no less than life-changing. Compact and constant power sources are necessary to keep these devices running efficiently. Edwar Romero's Powering Biomedical Devices reviews the background, current technologies, and possible future developments of these power sources, examining not only the types of biomedical power sources available (macro, mini, MEMS, and nano), but also what they power (such as prostheses, insulin pumps, and muscular and neural stimulators), and how they work (covering batteries, biofluids, kinetic and thermal energy, and telemetry). The book also looks at challenges such as energy generation efficiency, energy density, rectification, and energy storage and management. A final section on future trends rounds out the book. By briefly examining these key aspects, this book gives its readers a valuable overview of biomedical devices' power sources. A compact introduction to the vital topic of biomedical devices' power sources Reviews the background, current technologies, and possible future developments of biomedical power sources Short-format text allows for material that is clear, concise, and to-the-point Extensive references provided for further reading