The seminal reference on the care of laboratory and captiveanimals, The UFAW Handbook on the Care and Management ofLaboratory and Other Research Animals is a must-have for anyoneworking in this field. The UFAW Handbook has been thedefinitive text since 1947. Written for an international audience,it contains contributions from experts from around the world. The book focuses on best practice principles throughout, providingcomprehensive coverage, with all chapters being peer reviewed byanonymous referees. As well as addressing the husbandry oflaboratory animals, the content is also of great value to zoos andaquaria. Changes for the eighth edition: Revised and updated to reflect developments since publicationof the previous edition. New chapters on areas of growing concern, including: the 3Rs;phenotyping; statistics and experimental design; welfareassessment; legislation; training of people caring for lab animals;and euthanasia. All material combined into one volume for ease ofreference. This book is published on behalf of UFAW (The UniversitiesFederation for Animal Welfare), with whom we also publish theUFAW/Wiley-Blackwell Animal Welfare Book Series. This majorseries of books provides an authoritative source ofinformation on worldwide developments, current thinking and bestpractice in the field of animal welfare science and technology. Fordetails of all of the titles in the series see ahref="http://www.wiley.com/go/ufaw"www.wiley.com/go/ufaw/a.
This bestseller has been an essential book for all those workingwith laboratory animals since it was first published in 1994. This fourth edition retains all the classic features that have madeit a must-have reference including emphasis on best practice inorder to improve animal welfare. The contents have beenthoroughly updated and reorganised to make sure it is a reallypractical book for day-to-day use in the laboratory. Thefirst section of the book covers principles applicable to allspecies, for example husbandry, handling and the education andtraining required by scientists and technical staff working withanimals in the laboratory. Later chapters focus on specificspecies or groups of species. New to this edition: • Reflects changes in European legislation and theirimpact on national legislation • Covers recommendations for the education and trainingof those carrying out animal experiments across Europe • New chapters on ethical considerations and balancinganimal welfare with science • New information on environmental enrichment forlaboratory animals • Covers advancements in anaesthesia and analgesia andtechniques • Spiral bound for ease-of-use as a bench-topreference This book is ideal for all personnel carrying out scientificprocedures using animals, particularly during training and also forthe new researcher. It will also be essential reading forstudy directors designing research programmes, animal techniciansand veterinarians working with laboratory animal species.
The Welfare of Animals used in Research: Practice andEthics gives a complete and balanced overview of the issuessurrounding the use of animals in scientific research. Thefocus of the book is on the animal welfare implications and ethicsof animals in research. It covers the topics with sufficient depthto show a real understanding of varied and complex subjects, butconveys the information in a beautifully reader-friendlymanner. Key features: Provides those who are not working in the field with areasonable understanding as to why and how animals are used inresearch. Gives an introduction to the ethical issues involved in usinganimals, and explains how these are addressed in practice. Details the advances in animal welfare and the use anddevelopment of the 3Rs principles, and how these have becomefundamental to the everyday use and regulation of animals used inresearch. The focus is on principles making it suitable for aninternational audience. This book is a useful introduction to the issues involved inlaboratory animal welfare for those who intend to work in researchinvolving animals. It is also useful to prospective animal carestaff and animal welfare scientists, and to those involved inethical review. It will help inform debate amongst those who arenot involved in experimentation but who are interested in theissues. Published as a part of the prestigious Wiley-Blackwell – UFAWAnimal Welfare series. UFAW, founded 1926, is aninternationally recognised, independent, scientific and educationalanimal welfare charity. For full details of all titles available in the series, pleasevisit the UFAW AnimalWelfare series website.
Building upon the success of previous editions of the bestselling Handbook of Laboratory Animal Science, first published in 1994, this latest revision combines all three volumes in one definitive guide. It covers the essential principles and practices of Laboratory Animal Science as well as selected animal models in scientific disciplines where much progress has been made in recent years. Each individual chapter focuses on an important subdiscipline of laboratory animal science, and the chapters can be read and used as stand-alone texts, with only limited necessity to consult other chapters for information. With new contributors at the forefront of their fields, the book reflects the scientific and technological advances of the past decade. It also responds to advances in our understanding of animal behavior, emphasizing the importance of implementing the three Rs: replacing live animals with alternative methods, reducing the number of animals used, and refining techniques to minimize animal discomfort. This fourth edition will be useful all over the world as a textbook for laboratory animal science courses for postgraduate and undergraduate students and as a handbook for scientists who work with animals in their research, for university veterinarians, and for other specialists in laboratory animal science.
Animal Models for the Study of Human Disease, Second Edition, provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and biological sciences. Offering easily searchable advantages and disadvantages for each animal model and organized by disease topics, this resource aids researchers in finding the best animal model for research in human disease. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives, and animal ethics Covers a broad range of animal models used in research for human disease Contributed by leading experts across the globe Expanded coverage of diabetes and neurological diseases
Environmental enrichment is an integral part of animal care practices. Enrichment generally refers to items we provide to the animals to support their behavioral needs. It provides a way to functionally simulate the natural environment of captive animals, in an effort to increase opportunities for the expression of species-specific behaviors and decrease the occurrence of abnormal behaviors. Further, enrichment can also be a tool in the study of basic science questions, such as how environmental factors may affect disease etiology or progression. In this chapter, we will examine the use of enrichment in both applied and basic science contexts; as a welfare tool and as an experimental model.
The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries
The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century. By establishing an animal-centric view on housing and management, Animal-centric Care and Management: Enhancing Refinement in Biomedical Research takes Russell and Burch’s definition of Refinement as "elimination of inhumanities" and goes further. Rather than fitting animals into experimental conditions, it encourages readers to adjust conditions to better meet the behavioral, emotional, physical, and physiological needs and preferences of the animals. The team of expert authors, from the fields of laboratory animal science, ethology, biology as well as animal training, provide ideas for creating housing conditions and handling procedures that induce, to the best of current abilities and knowledge, a long-term positive state of mind in the animals under our care. This book is written for animal caretakers, animal health technicians, researchers, animal facility managers, laboratory animal veterinarians, and anyone who engages in work with living experimental animals or is interested in the continuous improvement of laboratory animal welfare. This interdisciplinary guide will act as a catalyst, resulting in multiple viewpoints and fields collaborating to optimize laboratory animal welfare.
The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the American College of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset (Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such as macaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. The marmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primate model to study a number of poorly understood disorders, like autism. Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications Includes contributions from renowned and international authors and editors Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series
This book offers an historical analysis of the culture of animal-dependent science in Britain from 1945 to the present, exploring key areas of animal experimentation such as warfare, medical science and law from a gendered perspective. Questioning the nature of knowledge production in this area, and how animal experimentation intersects with broader cultural norms and values concerning sex, and gender, it examines the impact of contemporary forms of capitalism on animal dependent science, its historical trajectory and gendered configuration. With close attention to the broad social context from the creation of the Welfare State and the loss of Empire, to the emergence of neoliberalism in the 1980s and its present day omnipotent manifestation, the author asks how animal experimentation and the use of nonhuman animals in specific areas of science is gendered and has implications for women. Drawing on a variety of sociological, philosophical, feminist and historical theories and engaging with a wealth of primary and secondary materials of scientific research of the time, Science, Gender and the Exploitation of Animals in Britain Since 1945 contends that there is a persistent, gendered ideology of animal use which remains inscribed within the policies of the British neoliberal state. As such, it will appeal to scholars of sociology, history and philosophy with interests in gender and the treatment of nonhuman animals.