Transplantation of the Pancreas

Transplantation of the Pancreas

Author: Rainer W.G. Gruessner

Publisher: Springer Science & Business Media

ISBN: 0387005897

Category: Medical

Page: 736

View: 676

Although pancreas transplants have been performed for more than 30 years, the last few years have witnessed significant growth in the options available for pancreas transplantation as well as subtantial improvements in outcome. It is therefore appropriate that a new text summarize the recent advances and put forth the standard of future care. Transplantation of the Pancreas, edited by Drs. Gruessner and Sutherland fulfills this mission by providing a state-of-the-art, definitive reference work on pancreas transplantation for transplant surgeons and physicians as well as for endocrinologists, diabetologists, nephrologists, and neurologist. The editors, from the renowned University of Minnesota Transplant Division and the Diabetes Institute, have assembled a group of renowned experts to provide an all inclusive overview of pancreas transplantation. The text features insights on the pathophysiology of diabetes mellitus and the limitations of nontransplant treatments, highlights experimental research and clinical history of pancreas transplantation, and compares and contrasts different surgical procedures. The discussions detail the broad spectrum of posttransplant complications and their treatments, which frequently require skills in general, vascular, and laparoscopic surgery, interventional radiology, critical care, and infectious disease. Chapters on immunosuppression, immunology, pathology, long-term outcome, quality of life, and cost-effectiveness focus on issues unique to pancreas recipients. Evolving areas, such as pretransplant evaluation of pancreas transplant candidates, living donation, and the current status of islet transplantation are discussed. Augmented by more than 280 illustrations, including full color line drawings created exclusively for the text, this book is the standard reference for all transplant professionals as well as all physicians caring for diabetic patients.

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas

Author: Giuseppe Orlando

Publisher: Academic Press

ISBN: 9780128148327

Category: Science

Page: 560

View: 183

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 2, sets a new standard in transplant and regenerative medicine. The book details the state-of-the-art in modern islet auto-transplantation, also discussing current progress in regenerative medicine research in diabetes medicine. Regenerative medicine is changing the premise of solid organ transplantation, hence this volume catalogs technologies being developed and methods being implemented. Bioengineering and regenerating beta cells, clinical pancreas and islet transplantation, tissue engineering, biomaterial sciences, stem cell biology and developmental biology are all addressed and applied directly to diabetes medicine. Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation Addresses imaging, treatment, scaffold technology, the use of stem cells to generate insulin, 3D printing, and more Offers an update on the progress of regenerative medicine research aimed at beta cell replacement for the treatment of diabetes

International Handbook of Pancreas Transplantation

International Handbook of Pancreas Transplantation

Author: Jean-Michel Dubernard

Publisher: Springer

ISBN: UOM:39015019567505

Category: Medical

Page: 570

View: 760

A synthetic review of the work done in the past ten years in the management of the complicated diabetic patient, gathering the experiences of the teams which have participated in promoting this method of endocrine replacement therapy and showing the problems yet to be solved. Emphasis is placed on t

Pancreas Transplantation

Pancreas Transplantation

Author: Luis H. Toledo-Pereyra

Publisher: Springer

ISBN: UOM:39015013217321

Category: Medical

Page: 298

View: 675

In December, 1966, two patients dying of months after the transplants had been per uremia as a result of diabetic kidney disease formed. This was long enough, however, to were offered a small chance of survival. Ac establish unequivocally in both patients cording to the thinking of the time, it was that an endocrine organ, the pancreas, could inappropriate-and perhaps even unethical function normally and for many days as a to offer them either chronic hemodialysis or human-to-human graft. The patients had kidney transplantation. These were considered become normoglycemic independent of insulin a waste of effort because it was believed that injections. scarce medical resources should not be spent The possible long-term benefits of restoring on patients, uremic or not, whose chances of insulin function were hotly argued then, and surviving for more than a few months were they have not been fully determined 20 years thought to be very small. Reduced to its later. It seems to me now, however, that the essence, the idea was that diabetic patients basic premise is sounder than I realized in were terrible risks and would remain so even if 1966: if one could restore an effective, norm the uremia were corrected.

Pancreas Transplantation – the Asian Experience

Pancreas Transplantation – the Asian Experience

Author: Duck-Jong Han

Publisher: Springer Nature

ISBN: 9789811645976

Category: Medical

Page: 239

View: 922

This book is the first to provide a thorough overview of the experience of pancreas transplantation in Asian countries, including in particular Korea, Taiwan, and Japan. Recent trends are identified and attention drawn to differences in comparison with the United States and Europe. Such differences relate, for example, to the history of pancreas transplantation, the operative procedure, and the organ-sharing system. In addition, the insulin-secreting ability of pancreatic islet cells is thought to vary depending on race. Beyond these aspects, the coverage also encompasses ABO-incompatible living donor pancreas transplantation, which is very rarely performed elsewhere in the world. By introducing the number, technique, and outcomes of pancreas transplantation in Asian countries, the book will hopefully further stimulate the pancreas transplantation program in this region and beyond. It will be of value for all medical professionals in the field and will be informative for diabetic patients receiving insulin treatment in Asia.

Transplantation of the Pancreas

Transplantation of the Pancreas

Author: Rainer W. G. Gruessner

Publisher: Springer

ISBN: 3031209982

Category: Medical

Page: 0

View: 567

As the 1st edition was, the 2nd edition will also be the definitive text on Pancreas Transplantation. As stated in a review of the 1st edition in the New England Journal of Medicine (353;14:2005) this text “is...a complete reference text in the field of pancreatic transplantation [with]....excellent chapters...[and] excellent color illustrations of operative techniques.” This second edition is dedicated to David E.R. Sutherland, considered the “father” of pancreas transplantation. This textbook is the primary reference on pancreas transplantation for transplant surgeons (established and in-training), pancreas and HPB surgeons, diabetologists, endocrinologists, gastroenterologists, pancreatologists and other health professionals with a focus on transplantation and diabetes (cardiologists, neurologists, urologists, ophthalmologists). The 2nd edition is enlarged, updated and improved. It consists of 11 sections and a total of 50 chapters (of which 16 chapters have subchapters). The chapter authors are all considered international leaders in their fields and represent institutions from 4 continents (America: USA, Argentina, Brazil, Canada; Europe: Belgium, France, Germany, Italy, Norway, Spain, Switzerland, The Netherlands, UK ; Asia: China, Japan, South Korea, Russian Federation; Australia). Compared to the 1st edition, the 2nd edition is organized in sections according to specific topics. The number of chapters has doubled. The number of national and international contributors has also almost doubled. Since the publication of the 1st edition in 2004, substantial progress has been made in Pancreas Transplantation specifically in regards to standardization of operative techniques and immunosuppression; significant improvements in patient and graft survival rates; and improved diagnosis and therapy of graft rejection and recurrence of disease. Pancreas transplants are no longer primarily performed in the USA and Europe for Type 1 Diabetes Mellitus: over the past 15 years, they have been performed with increasing frequency worldwide and also for Type 2 Diabetes Mellitus. The 2nd edition of this text covers all aspects of pancreas transplantation: Indication, recipient categories, surgical donor and recipient techniques, living donor transplantation, postoperative management and follow-up, post-transplant complications and malignancies, immunosuppression, treatment and diagnosis of rejection, impact on endocrine function and secondary complications of diabetes, recurrence of disease, quality of life, economic issues and overall outcome results. In addition, state-of-the art chapters focus on the classification, epidemiology and pathogenesis of type 1 and 2 diabetes mellitus as well as on other beta-cell replacement therapies including islet auto- and allo-transplantation.

Kidney and Pancreas Transplantation

Kidney and Pancreas Transplantation

Author: T. R. Srinivas

Publisher: Springer Science & Business Media

ISBN: 9781607616429

Category: Medical

Page: 441

View: 773

The transplant physicians and surgeons at Cleveland Clinic have collaborated to produce, Kidney and Pancreas Transplantation: A Practical Guide. This volume is devoted to kidney and pancreas transplantation and is well grounded in scientific principles, quantitative clinical reasoning, clinical pharmacology, tested clinical practices and overall clinical applicability. Also addressed are key aspects in the initiation, maintenance and sustained growth of viable clinical programs in kidney and pancreas transplantation. Kidney and Pancreas Transplantation: A Practical Guide will be of great value to transplant physicians as well as medical and surgical fellows who intend to pursue an interest in transplantation.

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas

Author: Giuseppe Orlando

Publisher: Academic Press

ISBN: 9780128148341

Category: Science

Page: 890

View: 589

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 1, sets a new standard in transplant and regenerative medicine. The book details the-state-of-the-art in modern whole pancreas and islet transplantation, including donor selection, immunosuppression, complications, allograft pathology, and more. As regenerative medicine is changing the premise of solid organ transplantation, this volume catalogs the technologies being developed and the methods being implemented to bioengineer or regenerate the endocrine pancreas in order to more effectively treat diabetes. Edited and authored by unparalleled leaders in the field, this new volume argues for a much needed synergy between organ transplantation and regenerative medicine. Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation Includes sections that address donor selection, immunosuppression, complications, allograft pathology, and more Offers an update on the progress of regenerative medicine research aimed at beta cells replacement in the treatment of diabetes

Pancreas and Islet Transplantation

Pancreas and Islet Transplantation

Author: Nadey S. Hakim

Publisher:

ISBN: UOM:39015055869286

Category: Medical

Page: 378

View: 560

Diabetes Mellitus is the principle cause of kidney failure and blindness in adults and leads to more cases of amputation and impotence than any other disease. It is one of the most common chronic diseases in childhood. The aims of pancreas or islet transplantation are to improve the quality of life of patients with insulin dependent diabetes mellitus and to ameliorate secondary complications. This book provides a comprehensive and international review of the recent advances in pancreas and islet transplantation. It covers surgical techniques, issues surrounding organ preservation, immunosuppression and the control of other complications, all of which contribute to the potential for such transplantations to evolve as the treatment of choice for insulin dependent diabetes. The editors have compiled a strong and international team of contribution authors. This book is essential reading for transplant surgeons and all those involved in researching or treating diabetes mellitus.